From Palermo: take the A29 highway heading on the Mazara del Vallo direction [follow the "Mazara del Vallo / uscita Castelvetrano"signals ] -from Castelvetrano, exit from the highway and follow the "Menfi" road directions- once you get in Menfi just follow the directions to Portopalo

From Trapani: take the A29 highway heading on the Mazara del Vallo direction [follow the "Mazara del Vallo / uscita Castelvetrano"signals until Castelvetrano, once in Castelvetrano exit from the highway and follow the "Menfi" road directions- once you get in Menfi just follow the directions to Portopalo

From Agrigento: take the S.S. heading to Trapani and follow until Menfi -once in Menfi , follow the normal road signs to Porto Palo.