[Genes: Structure and Regulation] Specificity Protein 1-dependent
Inhibition of the MnSOD gene by p53 was abolished when Sp1 sites on the MnSOD promoter were mutated or when the Sp1 protein was reduced by siRNA approaches. Because expression of MnSOD protects against cell death, our findings reveal a
Loss of Kruppel-Like Factor 4 Expression Contributes to Sp1
Enforced KLF4 expression repressed Sp1 expression at the promoter activity, mRNA, and protein levels. Moreover, a region within the proximal Sp1 promoter was identified to have overlapping KLF4- and Sp1-binding sites, to which KLF4 and
[Genes: Structure and Regulation] Regulatory Factor Interactions
Two of the protein-DNA complexes formed with liver extracts (C4 and C5) are due to the zinc finger proteins Sp1 and Sp3, respectively, whereas another complex (C6) is due to the cription factor RFX1. Two additional complexes (C1
[Molecular Basis Of Cell and Developmental Biology
Taken together, these results demonstrate that PGE2 plays an important role in regulating uterine and thus placental vascular development, acting through its receptors EP2 and EP4, provoking protein kinase A activation of AP2 and Sp1 as
Functional Difference of the SOX10 Mutant Proteins Responsible for
However, unlike 482ins6 protein, S135T protein synergistically activated EDNRB promoter with a cription factor Sp1, indicating that Sp1 could compensate the impaired function of a SOX10 mutant protein.
nrf2 mitochondria
Inhibition of PI3K-Akt reduced induction of HO-1 protein expression by H2O2 and smooth muscle cells: role of mitogen-activated protein kinases and Nrf2. elements for criptional factors NRF2 and Sp1. Northern blot analyses
[Genes: Structure and Regulation] Estrogen Receptor Isoform
identified retinoblastoma-binding protein 1 (RBBP1) as a major E2-regulated gene. an ER response element and a Sp1 site located within the first intron. utilizes both the Sp1 and estrogen response elements binding sites for
[Genes: Structure and Regulation] SerpinB2 Is an Inducible Host
The SerpinB2-mediated elevation of Rb protein levels appeared to be responsible for enhancing cription from the core promoter region of the LTR by relieving HDM2-mediated inhibition of Sp1 and/or by increasing the Sp1/Sp3
TWO UNEQUAULLY USUAL CHOICE
Coding for 389 amino acid residues of 45 kDa, pI of the deduced protein two gene-rich clusters is "not-self" that can induce glucose protein +1 or -1 domains of the Human cription factor Sp1. model for an antiparallel,
Serpinb2 is an inducible host factor involved in enhancing HIV-1
The enhancement of cription occurred in the presence and absence of Tat and was localized to the Sp1 sites in the core promoter region. The SerpinB2-mediated elevation of Rb protein levels lead to increased cription by

Binding of Phosphorylated Sp1 Protein to Tandem Sp1 Binding Sites
Sp1 protein-DNA complex formation was dependent on Sp1 phosphorylation. Gel mobility shift experiments using recombinant Sp1 protein (Promega, Madison,
Down-Regulation of Overexpressed Sp1 Protein in Human Fibrosarcoma
Down-Regulation of Overexpressed Sp1 Protein in Human Fibrosarcoma Cell Lines Inhibits Tumor Formation. Zhenjun Lou , Sandra O'Reilly , Hongyan Liang
TransBinding Sp1 Assay Kit
Figure 2: Typical results obtained by using the SP1 ELISA Kit. To test the detection sensitivity, active recombinant SP1 protein purified from E. coli was
Sp1 Protein (human) (recombinant) (HA) - ALX-201-106
The recombinant Sp1 protein can be employed in the following fields of research: i) The 778 amino acid human Sp1 protein contains a 81 amino acid
Lipopolysaccharide down-regulates Sp1 binding activity by
Immunoprecipitation-Western blot experiments demonstrated that LPS dephosphorylated Sp1 protein at serine and threonine residues but not at the tyrosine

TransBinding Sp1 Assay Kit
Figure 2: Typical results obtained by using the SP1 ELISA Kit. To test the detection sensitivity, active recombinant SP1 protein purified from E. coli was
TransBinding Sp1 Assay Kit
Sp1 represents the first identified and cloned protein of a family of cription The ubiquitously expressed Sp1 protein has been implicated in the
Sp1 Protein (human) (recombinant) (HA) - ALX-201-106
The recombinant Sp1 protein can be employed in the following fields of research: i) The 778 amino acid human Sp1 protein contains a 81 amino acid
Lipopolysaccharide down-regulates Sp1 binding activity by
Immunoprecipitation-Western blot experiments demonstrated that LPS dephosphorylated Sp1 protein at serine and threonine residues but not at the tyrosine
Transcription factor specificity protein 1 (Sp1) is the main
promoter analysis, indicating increased Sp1 protein binding to from NGF receptor TrkA to cription factor Sp1 protein
O glycosylation of an Sp1-derived peptide blocks known Sp1 protein
O glycosylation of an Sp1-derived peptide blocks known Sp1 protein interactions.In this paper we describe the use of the previously characterized
O glycosylation of an Sp1-derived peptide blocks known Sp1 protein
O glycosylation of an Sp1-derived peptide blocks known Sp1 protein interactions. M D Roos, K Su, J R Baker, and J E Kudlow. Department of Cell Biology,
Regulation of Constitutive Gene Expression through Interactions of
The region of residues -145 to -119 (CD/L) of the cathepsin D gene promoter contains a GC-rich motif that binds Sp1 protein and an adjacent pentanucleotide