[Membrane Transport, Structure, Function, and Biogenesis] CD4 and
To address this issue, we used a confocal microspectrofluorimetric approach to monitor fluorescence resonance energy fer at the cell plasma membrane between enhanced blue and green fluorescent proteins fused to CD4 and CCR5
[Membrane Transport, Structure, Function, and Biogenesis
Immunofluorescent analysis of Nedd4-2 in the adipocytes stably fected with the enhanced green fluorescent protein (EGFP)-tagged ATA2 showed the co-localization of Nedd4-2 and EGFP-ATA2 in the plasma membrane but not in the
[Membrane Transport, Structure, Function, and Biogenesis
The Na+/K+-ATPase maintains the physiological Na+ and K+ gradients across the plasma membrane in most animal cells. The functional unit of the ion pump is comprised of two mandatory subunits including the -subunit, which mediates ATP
[Membrane Transport, Structure, Function, and Biogenesis] Loss of
However, the precise molecular sites and the function for UT-A1 N-glycosylation Membrane fractionation of the plasma membrane, Golgi, and endoplasmic in both Golgi and plasma membrane compartments in WT but not in m1m2 cells.
[Membrane Transport, Structure, Function, and Biogenesis
Ubiquitylation occurs at the plasma membrane before internalization. Endocytosis of FcRIIA is dependent on clathrin but independent of the adaptor protein AP-2. These findings point to a novel mechanism for ubiquitylation and
[Lipids and Lipoproteins] ATP-binding Cassette Transporter A1
In addition, ABCA1 has been shown to influence functions of the plasma membrane, such as endocytosis and phagocytosis. Here, we report that ABCA1 expression results in a significant redistribution of cholesterol and sphingomyelin from
[CELL BIOLOGY AND SIGNAL TRANSDUCTION] Molecular Interactions of
Although precise functions of AGPs remain elusive, they are widely implicated in plant growth and development. A well characterized classical tomato AGP containing a glycosylphophatidylinositol (GPI) plasma membrane anchor sequence was
[Membrane Transport, Structure, Function, and Biogenesis] Caveolar
not cluster in membrane microdomains when added at higher concentrations (5–20 µ m ). leading to a reduced inclusion in plasma membrane microdomains and the sphingolipid stereochemistry in the formation of membrane microdomains
[Membrane Transport, Structure, Function, and Biogenesis] Distinct
We performed site-directed mutagenesis at this site and found that, although the mutants reduced channel activity, ENaC protein expression at the plasma membrane was unaffected. To deduce the role of M1 in the pore structure of ENaC,
[Molecular Basis Of Cell and Developmental Biology] A Novel
Here, we report a novel function of -aminobutyric acid receptors involving alveolar fluid homeostasis in adult lungs. We demonstrated the expression of functional ionotropic -aminobutyric acid receptors on the apical plasma membrane of
function+of+plasma+membrane: function+of+plasma+membrane