Enzyme inhibitor produces stable disease in patients with advanced
Preliminary trials of a MEK enzyme inhibitor have shown that it is capable of producing long-lasting stable disease in patients with advanced solid cancers. Tests showed that the drug inhibited key targets in the patients’ tumours,
Limerick #23887 on ACE, angiotensin-converting enzyme inhibitor
If your medic is knowledgy 'Bout pharmacology, He's hiding an ACE up his sleeve. Angiotensin-converting enzyme inhibitors are antihypertensive drugs that relax arteries and promote renal extraction of salt and water
S*BIO Presents Data at EORTC on Lead Histone Deacetylase Inhibitor
Announced the presentation of data on their lead histone deacetylase inhibitor, SB939, during the scientific sessions at the 18th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics.
Phase I Data for Exelixis' Kit Inhibitor XL820 Presented at EORTC
Announces that preliminary Phase I results were reported today from an ongoing trial of XL820, an oral small molecule compound which inhibits KIT, PDGF and VEGF and is designed to inhibit tumor growth and angiogenesis.
Aggresome induction by proteasome inhibitor bortezomib and {alpha
Histone deacetylase (HDAC) inhibitors have shown cytotoxicity as single agents in preclinical These data confirm the potential clinical benefit of combining HDAC inhibitors with proteasome inhibitors, and provide insight into the
A phase 2 trial of the FLT3 inhibitor lestaurtinib CEP701 as
We undertook a phase 2 trial of the FLT3-selective tyrosine kinase inhibitor lestaurtinib (CEP701) used as monotherapy in untreated older patients with AML not considered fit for intensive chemotherapy, irrespective of FLT3 mutation
Enzyme inhibitor produces stable disease in patients with advanced
Preliminary trials of a MEK enzyme inhibitor have shown that it is capable of producing long-lasting stable disease in patients with advanced solid cancers. Researchers told the 18th EORTC-NCI-AACR Symposium on "Molecular Targets and
Antileukemic Activity of Lysophosphatidic Acid Acyltransferase
Experimental Design: In this study, we investigated the effects of CT32228, a specific LPAAT-&szligbeta; inhibitor, on BCR-ABL-transformed cell lines and primary cells from patients with chronic myelogenous leukemia.
Schedule-Dependent Synergy between the Heat Shock Protein 90
Here, we examined the effect of the heat shock protein 90 (HSP90) inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin (DMAG) on doxorubicin-induced apoptosis in lymphoma. We aimed to establish the optimal schedule for
Falstatin, a Cysteine Protease Inhibitor of Plasmodium falciparum
We report here the identification of an endogenous cysteine protease inhibitor of Plasmodium falciparum, falstatin, based on modest homology with the Trypanosoma cruzi cysteine protease inhibitor chagasin.

Enzyme inhibitor - Wikipedia, the free encyclopedia
Irreversible inhibitors usually react with the enzyme and change it chemically. In mixed inhibition, the inhibitor can bind to the enzyme at the same
ACE inhibitor: Definition and Much More from Answers.com
ACE inhibitor n. Any of a class of drugs that cause vasodilation and are used to treat hypertension and heart failure.
CHFpatients.com - Ace Inhibitors For Heart Failure Explained
CHFpatients.com - Ace inhibitors explained in plain English - the primary drug treatment for heart failure.
COX-2 Inhibitor Use Halted in Cancer Prevention Trial, December 17
The National Institutes of Health (NIH) announced today that it has suspended the use of COX-2 inhibitor celecoxib (Celebrex™ Pfizer, Inc.) for all
eMedicine - Toxicity, Monoamine Oxidase Inhibitor : Article by
Toxicity, Monoamine Oxidase Inhibitor - Neurotransmitters are generally monoamines. When released into the synaptic space, neurotransmitters are either

ACE inhibitor: Definition and Much More from Answers.com
ACE inhibitor n. Any of a cl of drugs that cause vasodilation and are used to treat hypertension and heart failure.
CHFpatien.com Ace Inhibitors For Heart Failure Explained
CHFpatien.com Ace inhibitors explained in plain English the primary drug treatment for heart failure.
COX-2 Inhibitor Use Halted in Cancer Prevention Trial, December 17
The National Institutes of Health (NIH) announced today that it has suspended the use of COX-2 inhibitor celecoxib (Celebrex™ Pfizer, Inc.) for all
eMedicine Toxicity, Monoamine Oxidase Inhibitor : Article by
Toxicity, Monoamine Oxidase Inhibitor Netransmitters are generally monoamines. When released into the synaptic space, netransmitters are either
PROLYSIS
Welcome to PROLYSIS home page, intended as a Web resource for those interested in proteases and their natural or synthetic inhibitors.
Rust Inhibitor Coating & Produc Rust Paint & Preventative
Stop Rust and Corrosion with Rust Bullet-a rust repair rust remover corrosion inhibitor, which ac as a rust paint corrosion solution industrial coating.
MedlinePlus Drug Information: Antidepressan, Monoamine Oxidase
Antidepressan Monoamine Oxidase (MAO) Inhibitor(Systemic) Monoamine oxidase (MAO) inhibitors are used to relieve certain types of mental depression.
PLoS Pathogens: Carrageenan Is a Potent Inhibitor of
Despite these apparent chemical similarities to the noninhibitory chondroitin 4-sulfate, κ-carrageenan was an ely potent inhibitor,