The Brotherhoods originated in Savona after 1260, with their seat on the "Priamar" promontory.
At first, the were free from the hierarchical power of the church, even if they had penitential, charitable and mutual aid purposes.
The beginning of 1400 marked the moment of their major developement because the Brotherhoods got identified with the Trade Guilds.
Actually in the corporative "statutes" of craftsmen several articles are about the chapels and churches were the brothers used to meet.
Afterwards the Brotherhoods changed, mainly devoting themselves to prayng in their respective Oratories, besides the usually activities of social solidarity, the building of hospitals and the institution of pawnshops to assist the poor.