Methadone treatment in the General Practitioner Surgery. An example of Clinical Governance.

Additions aspects of an illness

 

 

A.  Michelazzi* – F.Vecchiet **.  (Trieste,Italy)

 

 

Before describing the results of the study carried out in Trieste, Italy, with a group of general practitioners involved in the treatment of heroin addicts, I think it is important to make a few preliminary comments.

Since 1994, around 50 family doctors have been treating heroin addicts in the Trieste area, and our total case-load is about 250 patients.

At the beginning, our day-to-day practice was disorganized,  haphazard and perhaps also rather improvised. It was made possible by a national referendum held in Italy in 1993, which changed the existing law on narcotics (Law 309) and made it possible for general practitioners to prescribe the substitute drug methadone.

Our original aim was, and still is, to make sure that patients who have been diagnosed as heroin addicts receive a personalized form of treatment. In fact, we regard heroin addiction as a chronic illness at risk of relapse, which should be treated with every instrument legitimate from the scientific point of view.

The predominant situation in Italy was, and still is, a situation whereby the law gives the monopoly for treating addicts to the Public Services for Drug Addictions. The result has been a concentration of these patients in large centres, which we had no hesitation in describing as “drug-addict asylums” on a par with those “lunatic asylums” which once existed in Italy (and which still exist in some parts of the world), where people thought to be suffering from some form of mild or severe mental illness were locked up.

The drawbacks of such a situation are obvious: the difficulty involved in personalizing treatment, the risk of a poor quality doctor-patient relationship, the abnormal change in identity and habits, the patient’s limited autonomy as regards timetabling of treatment, with repercussions for employment opportunities, and finally, the isolation of the staff working in the dedicated facility from the other treatment services available in the area.

 

Our role has been crucial in giving new choices to patients with heroin addiction, and by doing so, restoring their dignity and their right to a choice of treatment, a right which we felt they had been denied arbitrarily. (1)

In the case of madness, when the doors of the lunatic asylums were opened it emerged that many of the attitudes and kinds of behaviour considered part of the clinical picture were actually induced by the institutional setting; similarly, it soon became clear in our case that certain features attributed to drug addiction in itself were in fact a consequence of the institutional pressure the patients were subjected to.(2) In fact, the unreliability and aggressiveness, the self-harming behaviour and extreme self-centredness, but also certain antisocial or borderline personality traits  disappeared or became much less obvious, once our subjects began to be treated properly, in a different context which they preferred.

 

We realised very soon that we had to make sure our everyday practice was evidence-based, and provide ourselves with a governance which would make it perfectly legitimate for us treat heroin addicts. For this reason, to be sure we used, doses, and treatment protocols approved by the scientific community, we began collaborating almost immediately with the Italian Association for Addictions (SITD) and the University of Pisa, and also with our local Regional Centre for Training in General Medicine (now Primary Care).

 

 

 

At the same time, we set up a treatment network throughout the area, which involved agreeing on our treatment protocols with the Public Service for Drug Addictions, as well as working in some district health centres (our city is divided into four health districts) in order to handle the various types of patient (those posing fewer or greater problems).

 

With this very aim of better identifying the characteristics of those patients most “suited” to  treatment in the family doctor’s surgery, we designed a study together with our Centre for Training in General Medicine and the University of Pisa. For three years, we collected the data regarding 33 of our patients, chosen at random from those followed by approximately 20 family doctors.

The study, which will be published this year, analysed the baseline-endpoint variations in a series of variables considered relevant for indicating the factors predictive of a positive outcome (measured by retention rate, by substance use, by overall clinical improvement, by quality of life, and by abnormal psychological symptoms).

 

Aware of the limited number of patients involved, but convinced of the usefulness of the work, also as an example of clinical governance, we decided to process the data for statistical purposes. Without going into detail, it emerged that during the period under observation, no treatment was stopped because of violent behaviour, no patient was hospitalized, and there were no deaths from overdose. The baseline-endpoint differences were significant for all the substances analysed. Compared to their starting point, all of those patients who stayed in the treatment programme showed improvement, and their craving for heroin, alcohol and cocaine significantly diminished. In these non drop-outs, all the dimensions investigated using the SCL 90 scale improved (depression factors – paranoid ideas and somatization, psychosis), as did quality of life.

 

As regards the factors predictive of response to treatment, demographic factors were not predictive, and neither was an history of multi-substance use (polyabuse) or a clinical history of heroin abuse whereas the presence of a double diagnosis (especially of a bipolar disorder), and more serious illness at the beginning, were predictive of dropping out of treatment. Moreover, among the drop-outs, the abnormal psychological symptoms were more serious, and linked to obsessive-compulsive disorders, depression and aggressiveness. Also they had more socialization problems, and worse relationship with their partners-spouses.

Finally, the non drop-outs were treated with higher stabilizing doses  (and not low doses).

 

These results, though referring to a small number of patients, confirm our opinion of the importance of certain structural aspects of our practice. Firstly, the importance of training, which enables the general practitioner to identify certain aspects of the patient-addict, such as psychiatric co-morbidity , as unfavourable prognostic factors for successful treatment in the doctor’s surgery. Secondly, the importance of the link with the Public Service for Drug Addictions, which can provide invaluable assistance in the handling of these patients; its possible organisational models may be different, but this is not the place to discuss them. Suffice it to say that the law in force in Italy is totally inadequate for fostering good practice on the part of family doctors: it presently seems to require that every treatment started, and any change in dose must be accompanied every three months by a treatment plan done by the Public Service for Addictions, and prescriptions which in some cases must not exceed two boxes of methadone per prescription; this burdens the family doctor with pointless red tape, and ends up limiting the doctor’s professional responsability and freedom to treat, once again to the detriment of the patient and his independence.

We also believe that this study shows the importance of governance, of an attention to good practice sensitive to the multiplicity of variables which this kind of treatment involves. Hence the professional commitment necessary and  hence the importance of financial incentives.

In conclusion, I would like to make a few observations about the importance of the form we give to an illness, when we consider it in relationship to the “small” institutions in which it is being treated. This applies especially to those illnesses where the psychological and behavioural aspects are the most evident features, such as in madness, but also in heroin addiction and in others besides.

The degree of danger presented to themselves or to others, the negativism, the rejection, the ambivalence, but also the intensity of the compulsive or impulsive trait, are only a few of the aspects which are undoubtedly shaped by the type of institution responsable for treatment; they also shape the clinical form which we professionals give to the psychiatric or other illness connected to the addiction. But in my opinion, these considerations cannot be limited to the “microinstitutional” context alone; the “macroinstitutional”context must be considered too, and becomes vitally important for understanding the real nature of the illness we are dealing with. By ‘macroinstitutional’ context, I mean the social structure which affects us with its economic “laws” but also with its juridical laws and with its ethical and religious principles. (3)Only in this way can the neurobiology of psychiatric suffering or the suffering connected to addiction avoid the risk of becoming little more than a kind of ‘psychocosmetics’ with varying degrees of sophistication. This helps to explain why the incidence of certain disorders, such as conversion hysteria or obsessive-compulsive disorder, changes, in correlation with the form of illness assigned to them (whether psychotic or psychosomatic or paranoic).  It also helps to explain the reason for the great increase, in our contemporary globalized society, of the illnesses grouped together as the so-called  disorders of emptiness” (addictions, anorexia, bulimia, and borderline disorders as well as some of psychosexual identity).

As family doctors, it is our job to do what we can to alleviate the suffering of those who ask us for help, making responsible use of the scientific instruments available, trying to free ourselves from prejudice and whenever possible, taking into account the times and the social context in which we live.

 

Bibliography:

(1)General Practitioners and heroin addiction. Chronicle of a Medical practice. Michelazzi A. Vecchiet F. Cimolino T., Heroin Add § Rel. Clin. Probl. 1999; 1(2): 39-42

(2) Crimini di pace in Scritti II. Basaglia F. ,Einaudi, Torino, 1982; 330-336

(3)  Vocazione terapeutica e lotta di classe. Per un analisi critica del modello italiano. Basaglia F. Gallio G., testo presentato al Convegno franco-italiano di psichiatria (Parigi novembre 1979) organizzato dal C.N.R.; p.26